Overview

SCIENTIFIC SCORE
Questionable
Based on 6 Researches
6.3
USERS' SCORE
Good
Based on 12 Reviews
8.5
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
L-Lysine (as L-lysine HCl) (Free Form)
500 mg
**

Top Medical Research Studies

8
Lysine helps reduce cold sore outbreaks
We examined the effectiveness of long-term lysine supplementation for preventing cold sores, specifically in individuals with a history of frequent outbreaks. Over a 12-month period, twenty-six volunteers participated in a double-blind study, taking daily doses of 1,000 mg of lysine.

Our findings indicated that those taking lysine experienced significantly fewer lesions compared to the control group. Moreover, when participants stopped the supplementation, their outbreaks increased. Maintaining serum lysine levels above 165 nmol/ml appeared crucial for effectiveness, highlighting lysine's potential benefits in managing recurrent cold sores.
Read More
9
Lysine shows potential for herpes relief
We surveyed 1,543 individuals over six months to explore the impact of lysine on herpes infections, including cold sores. Participants averaged a daily dose of 936 mg of lysine. An impressive 84% reported that this supplement either prevented recurrence or reduced the frequency of outbreaks. When comparing symptoms, 79% found them severe without lysine, while only 8% felt the same when using it. Healing times improved dramatically—90% took six to 15 days to heal without lysine, but 83% healed in five days or less with it. Overall, 88% deemed lysine an effective treatment.
Read More
4
L-lysine lacks preventive effectiveness
We explored whether L-lysine can effectively prevent cold sores caused by the herpes simplex virus. Two researchers conducted a thorough literature review, examining various clinical studies.

Despite the interest, our findings indicate that L-lysine supplements, particularly less than 1 g per day, are ineffective for preventing outbreaks. Interestingly, higher doses, exceeding 3 g per day, were reported to enhance patients' overall experience with the condition.

However, we believe more extended studies focusing on higher dosages are necessary for conclusive results, especially for those with specific health concerns.
Read More

Most Useful Reviews

10
Herpes treatment
8 people found this helpful
Lysine is essential for those who suffer from herpes, preventing the virus from multiplying. After taking 1000 mg daily for three months, my herpes stopped appearing, even after colds or stress. It's been a year without any outbreaks. I recommend it to friends and family with herpes.
Read More
9
Effective supplement
4 people found this helpful
Initially sceptical, I found this supplement really effective. My cold sores are now a thing of the past. I take it during seasonal colds as a precaution, and my symptoms are much milder. Thank you, Solgar; I will continue using your products.
Read More
9
Cold sore solution
2 people found this helpful
I find this excellent for my cold sores; it clears them in 2-3 days. Solgar is a fantastic brand!
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 6 Researches
6.3
  • All Researches
9
L-lysine shows promise for cold sores
We examined the effects of L-lysine, paired with botanicals and nutrients, on cold sores caused by the herpes virus. In this pilot study, 30 participants tracked symptoms like itching and soreness, revealing impressive results. By the third day, 40% experienced complete healing, which rose to 87% by day six. While most showed significant improvement, a couple did not respond as well. Importantly, the study had no reported adverse effects, showing that L-lysine could effectively ease cold sore symptoms.
Read More
9
Lysine shows potential for herpes relief
We surveyed 1,543 individuals over six months to explore the impact of lysine on herpes infections, including cold sores. Participants averaged a daily dose of 936 mg of lysine. An impressive 84% reported that this supplement either prevented recurrence or reduced the frequency of outbreaks. When comparing symptoms, 79% found them severe without lysine, while only 8% felt the same when using it. Healing times improved dramatically—90% took six to 15 days to heal without lysine, but 83% healed in five days or less with it. Overall, 88% deemed lysine an effective treatment.
Read More
8
Lysine helps reduce cold sore outbreaks
We examined the effectiveness of long-term lysine supplementation for preventing cold sores, specifically in individuals with a history of frequent outbreaks. Over a 12-month period, twenty-six volunteers participated in a double-blind study, taking daily doses of 1,000 mg of lysine.

Our findings indicated that those taking lysine experienced significantly fewer lesions compared to the control group. Moreover, when participants stopped the supplementation, their outbreaks increased. Maintaining serum lysine levels above 165 nmol/ml appeared crucial for effectiveness, highlighting lysine's potential benefits in managing recurrent cold sores.
Read More
4
L-lysine helpful for prevention
We investigated how dietary changes and supplements affect skin conditions, focusing on cold sores. The review highlighted L-lysine’s benefits as a preventive measure, which may help ward off outbreaks. However, we found that it doesn't shorten the healing time of existing lesions. While there's plenty of anecdotal support, rigorous evidence remains limited for many dietary interventions in treating skin issues. Understanding these nutritional influences can guide us toward effective management options for cold sores.
Read More
4
L-lysine lacks preventive effectiveness
We explored whether L-lysine can effectively prevent cold sores caused by the herpes simplex virus. Two researchers conducted a thorough literature review, examining various clinical studies.

Despite the interest, our findings indicate that L-lysine supplements, particularly less than 1 g per day, are ineffective for preventing outbreaks. Interestingly, higher doses, exceeding 3 g per day, were reported to enhance patients' overall experience with the condition.

However, we believe more extended studies focusing on higher dosages are necessary for conclusive results, especially for those with specific health concerns.
Read More

User Reviews

USERS' SCORE
Good
Based on 12 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Herpes treatment
8 people found this helpful
Lysine is essential for those who suffer from herpes, preventing the virus from multiplying. After taking 1000 mg daily for three months, my herpes stopped appearing, even after colds or stress. It's been a year without any outbreaks. I recommend it to friends and family with herpes.
Read More
9
Effective supplement
4 people found this helpful
Initially sceptical, I found this supplement really effective. My cold sores are now a thing of the past. I take it during seasonal colds as a precaution, and my symptoms are much milder. Thank you, Solgar; I will continue using your products.
Read More
9
Cold sore solution
2 people found this helpful
I find this excellent for my cold sores; it clears them in 2-3 days. Solgar is a fantastic brand!
Read More
9
Quick recovery
2 people found this helpful
My resistance to cold sores has greatly improved, and when one does appear, recovery is much faster with reduced severity.
Read More
8
Faster healing
2 people found this helpful
At the first sign of a cold sore, I take this 2-3 times a day on an empty stomach. It helps the cold sore heal more quickly without the usual discomfort. I always keep it on hand.
Read More

Frequently Asked Questions

9
Cold sore solution
2 people found this helpful
I find this excellent for my cold sores; it clears them in 2-3 days. Solgar is a fantastic brand!
10
Herpes treatment
8 people found this helpful
Lysine is essential for those who suffer from herpes, preventing the virus from multiplying. After taking 1000 mg daily for three months, my herpes stopped appearing, even after colds or stress. It's been a year without any outbreaks. I recommend it to friends and family with herpes.
9
Quick recovery
2 people found this helpful
My resistance to cold sores has greatly improved, and when one does appear, recovery is much faster with reduced severity.
9
Effective supplement
4 people found this helpful
Initially sceptical, I found this supplement really effective. My cold sores are now a thing of the past. I take it during seasonal colds as a precaution, and my symptoms are much milder. Thank you, Solgar; I will continue using your products.
8
Faster healing
2 people found this helpful
At the first sign of a cold sore, I take this 2-3 times a day on an empty stomach. It helps the cold sore heal more quickly without the usual discomfort. I always keep it on hand.
7.5
Mouth skin improvement
1 people found this helpful
I always keep L-lysine ready for cold sore flare-ups and find my mouth skin health improves with this supplement. I would recommend it.
9
Effective combination
1 people found this helpful
When I take lysine at the first sign of herpes, the sore doesn't grow. I combine it with vitamin C and zinc for better results. This approach has helped me significantly.
7.5
Colds reduction
1 people found this helpful
I have been drinking this supplement for a short time, and I notice fewer colds after training while taking it alongside vitamins.
4
L-lysine helpful for prevention
We investigated how dietary changes and supplements affect skin conditions, focusing on cold sores. The review highlighted L-lysine’s benefits as a preventive measure, which may help ward off outbreaks. However, we found that it doesn't shorten the healing time of existing lesions. While there's plenty of anecdotal support, rigorous evidence remains limited for many dietary interventions in treating skin issues. Understanding these nutritional influences can guide us toward effective management options for cold sores.
4
L-lysine lacks preventive effectiveness
We explored whether L-lysine can effectively prevent cold sores caused by the herpes simplex virus. Two researchers conducted a thorough literature review, examining various clinical studies.

Despite the interest, our findings indicate that L-lysine supplements, particularly less than 1 g per day, are ineffective for preventing outbreaks. Interestingly, higher doses, exceeding 3 g per day, were reported to enhance patients' overall experience with the condition.

However, we believe more extended studies focusing on higher dosages are necessary for conclusive results, especially for those with specific health concerns.
9
Lysine shows potential for herpes relief
We surveyed 1,543 individuals over six months to explore the impact of lysine on herpes infections, including cold sores. Participants averaged a daily dose of 936 mg of lysine. An impressive 84% reported that this supplement either prevented recurrence or reduced the frequency of outbreaks. When comparing symptoms, 79% found them severe without lysine, while only 8% felt the same when using it. Healing times improved dramatically—90% took six to 15 days to heal without lysine, but 83% healed in five days or less with it. Overall, 88% deemed lysine an effective treatment.
8
Lysine helps reduce cold sore outbreaks
We examined the effectiveness of long-term lysine supplementation for preventing cold sores, specifically in individuals with a history of frequent outbreaks. Over a 12-month period, twenty-six volunteers participated in a double-blind study, taking daily doses of 1,000 mg of lysine.

Our findings indicated that those taking lysine experienced significantly fewer lesions compared to the control group. Moreover, when participants stopped the supplementation, their outbreaks increased. Maintaining serum lysine levels above 165 nmol/ml appeared crucial for effectiveness, highlighting lysine's potential benefits in managing recurrent cold sores.

References

  1. Jamgochian M, Alamgir M, Rao B. Diet in Dermatology: Review of Diet's Influence on the Conditions of Rosacea, Hidradenitis Suppurativa, Herpes Labialis, and Vitiligo. Am J Lifestyle Med. 2023;17:152. doi:10.1177/15598276211026592
  2. Mailoo VJ, Rampes S. Lysine for Herpes Simplex Prophylaxis: A Review of the Evidence. Integr Med (Encinitas). 2017;16:42.
  3. Singh BB, Udani J, Vinjamury SP, Der-Martirosian C, Gandhi S, et al. Safety and effectiveness of an L-lysine, zinc, and herbal-based product on the treatment of facial and circumoral herpes. Altern Med Rev. 2005;10:123.
  4. Thein DJ, Hurt WC. Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis. Oral Surg Oral Med Oral Pathol. 1984;58:659.
  5. Walsh DE, Griffith RS, Behforooz A. Subjective response to lysine in the therapy of herpes simplex. J Antimicrob Chemother. 1983;12:489.
  6. Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol. 1980;60:85.
image